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Kazusa DNA Research Institute & ProteinExpress Co., Ltd.
(Kazusa Akademia Park, Kisarazu-shi, Chiba Pref.)

Filmed on：2002-11-6

With its focus on the structural analysis of DNA, KDRI was inaugurated in 1994 as a leading facility of Kazusa Akademia Park, which Chiba Prefecture has been promoting as an international base of R&D in such high-tech fields as biotechnology, IT and new materials. It has already racked up some impressive scientific achievements in studies on human and plant DNA. In 1996, it decoded the genome of a blue-green alga (Synecholcystis), an accomplishment followed by the completion of decoding the genome of the herb mouse-ear cress (Arabidopsis Thaliana), at the end of the year 2000. Together with seven other cities and prefectures, KDRI is currently participating in the Tokyo Genome Bay Project, and the Urban Renaissance Headquarters, headed by Prime Minister Koizumi, designated it for one of its projects. Director Michio Oishi (Professor Emeritus, University of Tokyo) is also a member of the Premier-led Strategic Conference on Biotechnology.

Chiba Pref. is famous for producing shoyu, or soy sauce, and is the home of Higeta Shoyu Co., Ltd., one of Japan's major soy sauce makers. Higeta split off its Biotechnology R&D section and set it up as an independent company named ProteinExpress. In 2000 the PE opened its laboratory, Kazusa Lab, in Creation-Core Kazusa, an incubation facility of Kazusa Akademia Park. At present, the company is a world leader in terms of production of recombinant proteins using the Bacillus brevis protein expression system. Through an agreement reached with the prestigious KDRI the PE has gained access to their high quality and unique cDNA libraries.

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